With PrusaSlicer, you can print multiple models at once, each with slightly different settings. For example, with different infill or layer height.
Right-click (Advanced mode) on a model and pick either:
In the Expert mode, an additional Add settings option is available that lets you adjust settings such as speed, extrusion width, infill/perimeter overlap and more.
A new window will appear in the right panel called Object settings to modify. Changing these settings will affect only the relevant object and its instances. You can remove the settings overwrite by clicking on the red cross icon. When you do so, the global settings will once again be applied.